Search results for "rat olfactory mucosa"

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Odorant Metabolism Analysis by an Automated Ex Vivo Headspace Gas-Chromatography Method

2015

International audience; In the olfactory epithelium (OE), odorant metabolizing enzymes have the dual function of volatile component detoxification and active clearance of odorants from the perireceptor environment to respectively maintain the integrity of the tissues and the sensitivity of the detection. Although emphasized by recent studies, this enzymatic mechanism is poorly documented in mammals. Thus, olfactory metabolism has been characterized mainly in vitro and for a limited number of odorants. The automated ex vivo headspace gas-chromatography method that was developed here was validated to account for odorant olfactory metabolism. This method easily permits the measurement of the f…

0301 basic medicineodorant metabolizing enzymesPhysiology[SDV]Life Sciences [q-bio][ SDV.BA ] Life Sciences [q-bio]/Animal biologyheadspace gas-chromatographylocalizationAutomationBehavioral Neurosciencerabbit (Oryctolagus cuniculus)rat olfactory mucosaComputingMilieux_MISCELLANEOUSchemistry.chemical_classificationnewborn rabbit[SDV.BA]Life Sciences [q-bio]/Animal biologyperireceptor eventsmammary pheromoneSensory Systemsmedicine.anatomical_structureBiochemistryPheromonepartition-coefficientsRabbitsbiotransformationpsychological phenomena and processesolfactionChromatography GasOlfactionequilibrium03 medical and health sciencesOlfactory mucosaOlfactory MucosaPhysiology (medical)medicineAnimals[CHIM]Chemical Sciences[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyChromatographyMetabolismIn vitro030104 developmental biologyEnzymechemistry13. Climate actionOdorantsolfactory epitheliumacetateepitheliumOlfactory epitheliumEx vivonasal-mucosa

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